The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2008

Filed:

Jul. 18, 2006
Applicants:

Ernest Kun, Mill Valley, CA (US);

Jerome Mendeleyev, San Francisco, CA (US);

Carol Basbaurn, San Francisco, CA (US);

Hassan Lemjabbar-alaoui, Foster City, CA (US);

Valeria Ossovskaya, San Francisco, CA (US);

Inventors:

Ernest Kun, Mill Valley, CA (US);

Jerome Mendeleyev, San Francisco, CA (US);

Carol Basbaurn, San Francisco, CA (US);

Hassan Lemjabbar-Alaoui, Foster City, CA (US);

Valeria Ossovskaya, San Francisco, CA (US);

Assignee:

BiPAr Sciences, Inc., Brisbane, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A01N 43/16 (2006.01); C07D 217/22 (2006.01); C07D 311/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of treating ovarian cancer, endometrium cancer, cervical cancer, pancreatic cancer, bladder cancer, eve cancer, central nervous system cancer, thyroid cancer and lung cancer are disclosed. Specifically disclosed are methods of treating ovarian adenocarcinoma that has migrated into the abdominal cavity, a transitional cell carcinoma of the bladder, an epithelioid carcinoma in a pancreatic duct, an adenocarcinoma in a pancreatic duct, an adenocarcinoma in the cervical epithelium. The methods comprise administering to a patient a therapeutically effective amount of a compound of formula (Ia) wherein R, R, R, R, and Rare described herein, wherein at least two of the five R, R, R, R, and Rsubstituents are always hydrogen, at least one of the five substituents is always nitro, and at least one substituent positioned adjacent to a nitro is always iodo, and pharmaceutically acceptable salts thereof.


Find Patent Forward Citations

Loading…