The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2008

Filed:

Nov. 03, 2004
Applicants:

Nahm Ryune Cho, Daejeon, KR;

Jong Ho Lim, Daejeon, KR;

Jong Keun Kim, Daejeon, KR;

Inventors:

Nahm Ryune Cho, Daejeon, KR;

Jong Ho Lim, Daejeon, KR;

Jong Keun Kim, Daejeon, KR;

Assignee:

SK Corporation, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 41/00 (2006.01); C12P 17/10 (2006.01); C12N 9/12 (2006.01); C12N 9/14 (2006.01); C12N 9/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a method for preparing (S)-indoline-2-carboxylic acid and (S)-indoline-2-carboxylic acid methyl ester using an inexpensive industrially available enzyme capable of assuring superior optical purity and yield. At this time, the hydrolytic enzyme is selected from the group consisting of Savinase, Alcalase, Novozym 243, Everlase, Esperase, Protease 7 and Acylase, whereby (S)-indoline-2-carboxylic acid and methyl ester thereof having an optical purity of at least 99% e.e. can be obtained through a simplified preparation process, thus generating economic benefits.


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