The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2008

Filed:

Mar. 28, 2005
Applicants:

Kazuya Matsumoto, Boston, MA (US);

Yasushi Kazuno, Sanbu-gun, JP;

Norikazu Higashimura, Mobara, JP;

Toshihisa Ohshima, Tokushima, JP;

Haruhiko Sakuraba, Tokushima, JP;

Inventors:

Kazuya Matsumoto, Boston, MA (US);

Yasushi Kazuno, Sanbu-gun, JP;

Norikazu Higashimura, Mobara, JP;

Toshihisa Ohshima, Tokushima, JP;

Haruhiko Sakuraba, Tokushima, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 45/72 (2006.01);
U.S. Cl.
CPC ...
Abstract

An industrial process for producing hydroxyaldehydes efficiently, by solving the problems of conventional DERA, such as low stability against aldehydes, low catalytic activity for aldol condensation, and the difficulty of controlling the number of acetaldehyde molecules to be condensed, is provided. According to the process, aldol condensation of a substituted or unsubstituted aliphatic aldehyde compound having 2 to 6 carbon atoms with acetaldehyde is conducted by using D-2-deoxyribose-5-phosphate aldolase which is highly stable against aldehydes and has high catalytic activity for aldol condensation, whereby a hydroxyaldehyde compound having the number of carbon atoms increased by two or four can be produced.


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