The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2008

Filed:

Jun. 29, 2006
Applicants:

Philippe Burnier, Maisons-Laffitte, FR;

Jacques Froissant, Brevainville, FR;

Benoit Marabout, Massy, FR;

Frank Marguet, Verrieres-le-Buisson, FR;

Frederic Puech, La Celle Saint Cloud, FR;

Inventors:

Philippe Burnier, Maisons-Laffitte, FR;

Jacques Froissant, Brevainville, FR;

Benoit Marabout, Massy, FR;

Frank Marguet, Verrieres-le-Buisson, FR;

Frederic Puech, La Celle Saint Cloud, FR;

Assignee:

Sanofi-Aventis, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/02 (2006.01); C07D 209/42 (2006.01); A61K 31/503 (2006.01);
U.S. Cl.
CPC ...
Abstract

A subject-matter of the invention is the compounds of general formula (I) in which X represents a hydrogen or halogen atom; Rrepresents a hydrogen atom or a (C-C)alkyl group; Rand Reach represent, independently of one another, a hydrogen atom or a (C-C)alkyl group or else Rand Rform, with the nitrogen atom which carries them, a pyrrolidinyl, piperidinyl, morpholinyl or 4-alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, 1-oxidopyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl or pyridazinyl type, it being possible for the heteroaromatic group to carry one or more halogen atoms and/or one or more (C-C)alkyl or (C-C)alkoxy groups; in the form of bases, of addition salts with acids, of solvates or of hydrates, the pharmaceutical compositions comprising them, processes for their preparation and synthetic intermediates.


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