The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2008
Filed:
Feb. 28, 2002
Peter Raymond Flatt, Portrush, GB;
Finbarr Paul Mary O'harte, Portstewart, GB;
Peter Raymond Flatt, Portrush, GB;
Finbarr Paul Mary O'Harte, Portstewart, GB;
University of Ulster, Coleraine, County Londonderry, GB;
Abstract
The invention provides a peptide based on biologically active CCK-8 having improved characteristics for the treatment of obesity and/or type 2 diabetes wherein the primary structure of CCK-8 is: AspTyr(SOH)-MetGlyTrpMetAspPheamide (SEQ ID NO:1) and wherein the peptide has at least one amino add substitution and/or modification and is not Asp-glucitol CCK-8. The invention also provides the use of the peptide in the preparation of a medicament to inhibit food intake, induce satiety, stimulate insulin secretion, moderate blood glucose excursions, enhance glucose disposal and/or exhibit enhanced stability in plasma compared to native CCK-8 and/or for treatment of obesity and/or type 2 diabetes.