The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2008

Filed:

Mar. 13, 2006
Applicants:

Dilijeet Singh Athwal, London, GB;

Derek Thomas Brown, Beenham, GB;

Andrew Neil Charles Weir, Reading, GB;

Andrew George Popplewell, Staines, GB;

Andrew Paul Chapman, Hampton, GB;

David John King, Belmont, CA (US);

Inventors:

Dilijeet Singh Athwal, London, GB;

Derek Thomas Brown, Beenham, GB;

Andrew Neil Charles Weir, Reading, GB;

Andrew George Popplewell, Staines, GB;

Andrew Paul Chapman, Hampton, GB;

David John King, Belmont, CA (US);

Assignee:

UCB Pharma S.A., Brussels, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/08 (2006.01); C07K 16/00 (2006.01); A61K 39/395 (2006.01); C12P 21/04 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNFα. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNFα.


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