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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7402436 B1

PDFFull Text
Date of Patent:
Jul. 22, 2008

Filed:

May. 03, 2005

Lentiviral vectors for site-specific gene insertion

Applicants:

Jiing-kuan Yee, Arcadia, CA (US);

Gilles Michel, Galveston, TX (US);

Inventors:

Jiing-Kuan Yee, Arcadia, CA (US);

Gilles Michel, Galveston, TX (US);

Assignee:

City of Hope, Duarte, CA (US);

Attorneys:

Michael J. Wise

Perkins Coie LLP

Primary Examiner:

David Guzo

Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/64 (2006.01); C12N 15/867 (2006.01); C07K 14/155 (2006.01); C07K 14/195 (2006.01); C07K 19/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Murine leukemia virus (MLV) and lentivirus vectors have been used previously to deliver genes to hematopoietic stem cells (HSCs) in human gene therapy trials. However, these vectors integrate randomly into the host genome, leading to disruption or inactivation of vital host genes. The present invention discloses a novel lentiviral vector system that overcomes this problem by integrating into a host genome in a site-specific manner.

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Quick Actions:

Yee, Jiing-Kuan. (2008). Lentiviral vectors for site-specific gene insertion (U.S. Patent No. 7402436). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7402436

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