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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7402417 B1

PDFFull Text
Expired
Date of Patent:
Jul. 22, 2008

Filed:

Jul. 21, 2004

P450 oxygenases and methods of use

Applicants:

Rodney B. Croteau, Pullman, WA (US);

Robert Long, Moscow, ID (US);

Stefan Jennewein, Alfdorf, DE;

Inventors:

Rodney B. Croteau, Pullman, WA (US);

Robert Long, Moscow, ID (US);

Stefan Jennewein, Alfdorf, DE;

Assignee:

Washington State University Research Foundation, Pullman, WA (US);

Attorneys:

Paula A. DeGrandis

Klarquist Sparkman, LLP

Primary Examiner:

Yong D Pak

Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12P 7/66 (2006.01); C12P 21/04 (2006.01); C12Q 1/26 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01); C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This disclosure provides the nucleic acid and protein sequences of novel P450 oxygenases that utilize, at least, taxoid substrates, including taxadiene isomers. The disclosed oxygenases, such as a taxoid 5α-hydroxylase, hydroxylate, at least, the C5 position of a taxoid. Also provided are methods of introducing oxygen at the C5 position of a taxoid and methods of producing the anti-cancer drug, paclitaxel (also known as Taxol™), and other taxoids, such as paclitaxel intermediates.

Find Patent Forward Citations

Croteau, Rodney. (2008). P450 oxygenases and methods of use (U.S. Patent No. 7402417). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7402417

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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