The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2008
Filed:
Mar. 22, 2005
Jean Louise Helom, Hillsdale, NJ (US);
Arkadiy Zinoviy Rubezhov, West Nyack, NY (US);
Anthony Scott Pilcher, Colchester, VT (US);
Bogdan Kazimierz Wilk, New City, NY (US);
Jean Louise Helom, Hillsdale, NJ (US);
Arkadiy Zinoviy Rubezhov, West Nyack, NY (US);
Anthony Scott Pilcher, Colchester, VT (US);
Bogdan Kazimierz Wilk, New City, NY (US);
Wyeth, Madison, NJ (US);
Abstract
The instant invention concerns processes for the production of pyrrole-2-carbonitriles such as 1-methylpyrrole-2-carbonitrile. Such processes preferably comprise the steps of reacting a pyrrole with chlorosulfonyl isocyanate in the presence of a solvent and contacting the resulting product with a molar excess of an amide such as N,N-dimethylformamide. The product of this contacting step is then contacted with a molar excess of an organic base to produce a precipitate and a solution phase. The precipitate is then separated from the solution phase and the corresponding pyrrole-2-carbonitrile is isolated from the resulting solution phase.