The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2008
Filed:
May. 18, 2006
Frederick Cohen, San Francisco, CA (US);
Wayne J. Fairbrother, Burlingame, CA (US);
Clifford Quan, Belmont, CA (US);
Daniel P. Sutherlin, South San Francisco, CA (US);
Beni B. Wolf, Redwood City, CA (US);
Frederick Cohen, San Francisco, CA (US);
Wayne J. Fairbrother, Burlingame, CA (US);
Clifford Quan, Belmont, CA (US);
Daniel P. Sutherlin, South San Francisco, CA (US);
Beni B. Wolf, Redwood City, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
Amino terminus-blocked peptide boronate compounds of Formulas I and II are useful for inhibiting Fibroblast Activation Protein (FAP) and other proteases, and for treating disorders mediated by FAP. Methods of using the amino terminus blocked peptide boronate compounds, and stereoisomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.