The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2008
Filed:
Oct. 24, 2003
Applicants:
Mark E. Duggan, Harleysville, PA (US);
Craig W. Lindsley, Schwenksville, PA (US);
Zhijian Zhao, Wilmington, DE;
Inventors:
Mark E. Duggan, Harleysville, PA (US);
Craig W. Lindsley, Schwenksville, PA (US);
Zhijian Zhao, Wilmington, DE;
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/50 (2006.01); A61K 31/497 (2006.01); C07D 241/00 (2006.01); C07D 487/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is directed to compounds which contain a five-membered heterocyclic ring fused to a substituted pyrazine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.