The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2008
Filed:
Sep. 11, 2001
Applicants:
Kenneth R. Chien, La Jolla, CA (US);
Masahiko Hoshijma, San Diego, CA (US);
John Ross, Jr., La Jolla, CA (US);
Yasuhiro Ikeda, Yamaguchi, JP;
Inventors:
Kenneth R. Chien, La Jolla, CA (US);
Masahiko Hoshijma, San Diego, CA (US);
John Ross, Jr., La Jolla, CA (US);
Yasuhiro Ikeda, Yamaguchi, JP;
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A01N 63/00 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods for the delivery of genes to improve cardiac function including the use of viral vectors, isolation of the heart from systemic circulation, and induction of hypothermia/cardiac arrest are described. The method results in high-level, long-term expression of reporter genes and enhanced cardiac function in hamster models of heart disease.