The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2008

Filed:

Sep. 25, 2006
Applicants:

Paul W. Wedeking, Pennington, NJ (US);

Ruth E. Wager, Rockville, MD (US);

Thangavel Arunachalam, Plainsboro, NJ (US);

Kondareddiar Ramalingam, Dayton, NJ (US);

Karen E. Linder, Kingston, NJ (US);

Ramachandran S. Ranganathan, Princeton, NJ (US);

Adrian D. Nunn, Lambertville, NJ (US);

Nataranjan Raju, Kendall Park, NJ (US);

Michael F. Tweedle, Princeton, NJ (US);

Inventors:

Paul W. Wedeking, Pennington, NJ (US);

Ruth E. Wager, Rockville, MD (US);

Thangavel Arunachalam, Plainsboro, NJ (US);

Kondareddiar Ramalingam, Dayton, NJ (US);

Karen E. Linder, Kingston, NJ (US);

Ramachandran S. Ranganathan, Princeton, NJ (US);

Adrian D. Nunn, Lambertville, NJ (US);

Nataranjan Raju, Kendall Park, NJ (US);

Michael F. Tweedle, Princeton, NJ (US);

Assignee:

Bracco International B.V., Amsterdam, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Diagnostic and therapeutic compositions in the form of complexes for enhancing transmembrane transport of a diagnostic or therapeutic agent and methods for their use. The complexes contain the α, γ, or bis isomers of folate receptor-binding analogs of folate, a metal chelated by a ligand, and in one embodiment, a chemotherapeutic agent.


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