The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2008
Filed:
Feb. 27, 2004
Saiko Hosokawa, Tokyo, JP;
Masahiko Aoki, Tokyo, JP;
Yoko Hirakawa, Tokyo, JP;
Seima Itami, Tokyo, JP;
Hiroe Umeki, Tokyo, JP;
Yoshiro Saikawa, Tokyo, JP;
Koichiro Kumai, Tokyo, JP;
Kazumasa Fukuda, Tokyo, JP;
Saiko Hosokawa, Tokyo, JP;
Masahiko Aoki, Tokyo, JP;
Yoko Hirakawa, Tokyo, JP;
Seima Itami, Tokyo, JP;
Hiroe Umeki, Tokyo, JP;
Yoshiro Saikawa, Tokyo, JP;
Koichiro Kumai, Tokyo, JP;
Kazumasa Fukuda, Tokyo, JP;
Mitsubishi Pharma Corporation, Osaka, JP;
Keio University, Tokyo, JP;
Abstract
A novel human monoclonal antibody specifically recognizing cancer cells such as non-small cell lung cancer, pancreatic cancer and gastric cancer cells is produced by hybridomas which are obtained by fusing lymphocytes derived from a cancer tissue of a cancer patient with mouse myeloma cells. An anti-cancer drug is obtained by using the antibody alone or anchoring the antibody on the surface of a liposome containing a toxin or an anti-cancer drug encapsulated therein. More specifically, an anti-cancer drug is obtained by using an antibody, in which variable region of its heavy chain comprises the amino acid sequence of SEQ ID NO: 115 and variable region of the light chain comprises the amino acid sequence of SEQ ID NO: 117, alone or anchoring the antibody on the surface of a liposome containing a toxin or an anti-cancer drug encapsulated therein.