The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2008
Filed:
Nov. 06, 2000
Applicants:
Jon A. Wolff, Madison, WI (US);
Vladimir G. Budker, Middleton, WI (US);
Inventors:
Jon A. Wolff, Madison, WI (US);
Vladimir G. Budker, Middleton, WI (US);
Assignee:
Miris Bio Corporation, Madison, WI (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A01N 43/04 (2006.01); A61K 48/00 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed is a process for transfecting genetic material into a mammalian cell to alter endogenous properties of the cell. The process comprises designing a polynucleotide for transfection. Then the polynucleotide is inserted into a mammalian blood vessel. Prior to insertion, subsequent to insertion, or concurrent with insertion the permability of the vessel is increased using an exterior cuff and immunosuppression is applied thereby the genetic material is delivered to the parenchymal cell.