The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2008
Filed:
Dec. 14, 2004
David A. Estell, San Mateo, CA (US);
Grant C. Ganshaw, Tracy, CA (US);
Christian Paech, Daly City, CA (US);
Sigrid Paech, Daly City, CA (US);
David A. Estell, San Mateo, CA (US);
Grant C. Ganshaw, Tracy, CA (US);
Christian Paech, Daly City, CA (US);
Sigrid Paech, Daly City, CA (US);
Genencor International, Inc., Palo Alto, CA (US);
Abstract
The present invention makes use of unique tags of a specific biopolymer that can be exploited for determining the concentration the biopolymer in crude solutions. In preferred embodiments the biopolymer is either a protein or a polynucleotide. Particularly, the invention provides a method for the determination and quantitation of biomolecules in crude mixtures by way of a separation technique in combination with mass spectroscopy. In one general embodiment, a target biomolecule is selected for analysis and an analog thereof is generated. Peak area integration of the peptide pairs provides a direct measure for the amount of target protein in the crude solution.