The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2008
Filed:
Mar. 31, 2004
Nicholas D. P. Cosford, San Diego, CA (US);
Dehua Huang, San Diego, CA (US);
Jeffrey R. Roppe, Temecula, CA (US);
Nicholas D. Smith, San Diego, CA (US);
Lida R. Tehrani, San Diego, CA (US);
Nicholas D. P. Cosford, San Diego, CA (US);
Dehua Huang, San Diego, CA (US);
Jeffrey R. Roppe, Temecula, CA (US);
Nicholas D. Smith, San Diego, CA (US);
Lida R. Tehrani, San Diego, CA (US);
Merck & Co. Inc., Rahway, NJ (US);
Abstract
Pyrrole compounds of Formula (I): and pharmaceutically acceptable salts thereof (where A, B, R, R, R, W, X, Y and Z are as defined herein), which are substituted directly, or by a bridge, with i) a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl and ii) another heteroaryl or aryl ring, with at least one of the rings being further substituted with another ring, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, panic, and bipolar disorder, as well as in the treatment of pain, Parkinson's disease, cognitive dysfunction, epilepsy, circadian rhythm disorders, drug addiction, drug abuse, drug withdrawal, obesity and other diseases