The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2008

Filed:

Jun. 17, 2005
Applicants:

Graham Beaton, Poway, CA (US);

Wilna (Willy) J Moree, San Diego, CA (US);

Florence Jovic, La Jolla, CA (US);

Timothy Coon, Carlsbad, CA (US);

Jinghua Yu, San Marcos, CA (US);

Inventors:

Graham Beaton, Poway, CA (US);

Wilna (Willy) J Moree, San Diego, CA (US);

Florence Jovic, La Jolla, CA (US);

Timothy Coon, Carlsbad, CA (US);

Jinghua Yu, San Marcos, CA (US);

Assignee:

Neurocrine Biosciences, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/425 (2006.01); A61K 31/381 (2006.01); C07D 277/20 (2006.01); C07D 333/52 (2006.01); C07D 409/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds having the following structure (I): including stereoisomers, prodrugs, and pharmaceutically acceptable salts, esters and solvates thereof, wherein R, R, R, R, L, Land n are as defined herein. Such compounds generally function as Hreceptor ligands, and thus have utility as sleep inducing agents. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.


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