The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2008
Filed:
Aug. 31, 2000
Øystein Rekdal, Tromsø, NO;
John Sigurd Svendsen, Tromsø, NO;
Mari Wikman, Tromsø, NO;
Terese Solstad, Tromsø, NO;
Nannan Yang, Tromsø, NO;
Øystein Rekdal, Tromsø, NO;
John Sigurd Svendsen, Tromsø, NO;
Mari Wikman, Tromsø, NO;
Terese Solstad, Tromsø, NO;
Nannan Yang, Tromsø, NO;
Lytix Biopharma, Tromso, NO;
Abstract
The present invention relates to a method of producing a bioactive peptide, wherein the peptide is 7 to 25 amino acids in length, has at least 3 cationic amino acids and is capable of forming an amphipathic α-helix, which method comprises identification of a cationic sector and division of the remaining part of the peptide into three further sectors which are substantially equal in size, and incorporation of at least 60% of the bulk and lipophilicity provided by the amino acid R groups into the sectors flanking the cationic sector; and to uses of the peptides produced thereby in therapy, particularly in the treatment of benign or malignant tumours.