The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2008
Filed:
Mar. 30, 2006
Applicants:
Qiong Cheng, Wilmington, DE (US);
Luan Tao, Haverstown, PA (US);
Inventors:
Qiong Cheng, Wilmington, DE (US);
Luan Tao, Haverstown, PA (US);
Assignee:
E.I. du Pont de Nemours and Company, Wimington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 23/00 (2006.01); C12N 5/10 (2006.01); C12N 1/21 (2006.01); C12N 15/00 (2006.01); C12N 5/14 (2006.01); C12N 1/12 (2006.01); C12N 1/11 (2006.01); C12N 1/13 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C07H 21/00 (2006.01); C12N 9/02 (2006.01); C12P 21/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
CrtW carotenoid ketolases are provided that are useful for the production of astaxanthin and other cyclic ketocarotenoids. The mutant ketolase genes of the present invention encode polypeptides characterized by an improvement in astaxanthin synthesis activity when converting cyclic hydroxylated carotenoid intermediates into astaxanthin. Expression of the mutant carotenoid ketolases in heterologous hosts enabled increased production of astaxanthin relative to theDC18 CrtW.