The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2008

Filed:

May. 31, 2006
Applicants:

Ramesh N. Patel, Bridgewater, NJ (US);

Linda Nga Hoong Chu, East Brunswick, NJ (US);

Robert M. Johnson, Whitehouse Station, NJ (US);

Zhiwei Guo, Franklin Park, NJ (US);

Yijun Chen, Belle Mead, NJ (US);

Steven L. Goldberg, Basking Ridge, NJ (US);

Ronald L. Hanson, Morris Plains, NJ (US);

Animesh Goswami, Plainsboro, NJ (US);

Kishta Katipally, Monmouth Junction, NJ (US);

Inventors:

Ramesh N. Patel, Bridgewater, NJ (US);

Linda Nga Hoong Chu, East Brunswick, NJ (US);

Robert M. Johnson, Whitehouse Station, NJ (US);

Zhiwei Guo, Franklin Park, NJ (US);

Yijun Chen, Belle Mead, NJ (US);

Steven L. Goldberg, Basking Ridge, NJ (US);

Ronald L. Hanson, Morris Plains, NJ (US);

Animesh Goswami, Plainsboro, NJ (US);

Kishta Katipally, Monmouth Junction, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 17/16 (2006.01); C07D 253/08 (2006.01); C12N 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a process for the enzymatic, stereoselective reduction of ketone compounds to provide chiral alcohols, for example the compound of formula Ib:


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