The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2008

Filed:

Jan. 05, 2006
Applicants:

Susan V. Cannon-carlson, Wayne, NJ (US);

Collette Cutler, Bloomingdale, NJ (US);

Gary J. Vellekamp, Glen Ridge, NJ (US);

Marcio Voloch, New York, NY (US);

Inventors:

Susan V. Cannon-Carlson, Wayne, NJ (US);

Collette Cutler, Bloomingdale, NJ (US);

Gary J. Vellekamp, Glen Ridge, NJ (US);

Marcio Voloch, New York, NY (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for purifying adenoviruses from a contaminated sample using a hydroxyapatite medium are provided. Sodium chloride concentrations present in buffers used throughout the method are at least 150 mM to prevent the adenovirus from irreversibly binding to the hydroxyapatite. Levels of contaminants and empty adenovirus capsids from samples purified by conventional purification techniques are further reduced to provide a highly pure adenovirus preparation.


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