The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2008
Filed:
Feb. 21, 2003
Applicants:
Robert J. Powell, Baltimore, MD (US);
George K. Lewis, Baltimore, MD (US);
David M. Hone, Ellicott City, MD (US);
Inventors:
Robert J. Powell, Baltimore, MD (US);
George K. Lewis, Baltimore, MD (US);
David M. Hone, Ellicott City, MD (US);
Assignee:
University of Maryland, Baltimore, Baltimore, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A61K 48/00 (2006.01); A61K 39/00 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said the animal cells with live invasive bacteria, wherein bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense RNA or a catalytic RNA.