The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2008
Filed:
Dec. 13, 2005
Parichehr Malherbe, Muttenz, CH;
Raffaello Masciadri, Basel, CH;
Roger David Norcross, Olsberg, CH;
Hasane Ratni, Habsheim, FR;
Andrew William Thomas, Birsfelden, CH;
Parichehr Malherbe, Muttenz, CH;
Raffaello Masciadri, Basel, CH;
Roger David Norcross, Olsberg, CH;
Hasane Ratni, Habsheim, FR;
Andrew William Thomas, Birsfelden, CH;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
The present invention relates to compounds of formula I wherein R, R, R, R, and Rare as defined in the specification. Compounds of the invention are active on the GABAB receptor and are useful for treating a variety of CNS disorders, including anxiety, depression, epilepsy, schizophrenia, cognitive disorders, spasticity-and skeletal muscle rigidity, spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis, cerebral palsy, neuropathic pain and craving associated with cocaine and nicotine, psychosis, panic disorder, posttraumatic stress disorders and gastro-intestinal disorders.