The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2008
Filed:
Jun. 11, 2002
Toni M. Kutchan, Halle, DE;
Meinhart H. Zenk, Halle, DE;
Torsten Grothe, Kuerten, DE;
Donald Danforth Plant Science Center, St. Louis, MO (US);
Abstract
This invention provides: (A) a protein the sequence of which is in FIG.(SEQ. ID n° 14), or a fragment thereof having at least 15 amino acids, or a variant thereof, having at least 70% identity with FIG.(SEQ. ID n° 14) over a length of at least 400 amino acids; (B) a peptide comprising a fragment of salutaridinol 7-O-acetyltransferase of at least 6 consecutive amino acids not present in other plant acetyltransferases as in FIG.(SEQ. IDs n° 8 to 12); (C) a nucleic acid (i) the sequence of which is in FIG.(SEQ. ID n° 13) or FIG.(SEQ. ID n° 15), or (ii) a fragment thereof of at least 45 nucleotides, or (iii) a variant thereof, having at least 70% identity with FIG.(SEQ. ID n° 13) or FIG.(SEQ. ID n° 15) over a length of at least 1200 bases, or (iv) a sequence complementary to (i), (ii) or (iii); or (v) the RNA equivalent of any of (i), (ii), or (iii); (D) a nucleic acid comprising a fragment of a salutaridinol 7-O-acetyltransferase gene of at least 18 consecutive nucleotides unique to the salutaridinol 7-O-acetyltransferase gene from the 5' or 3′ untranslated regions in FIG.(SEQ. ID n° 13), or a sequence complementary thereto. This invention also provides methods for producing pentacyclic morphinan alkaloids and thebaine.