The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2008
Filed:
Oct. 11, 2002
Jacques Fages, Albi, FR;
Bernard Freiss, Castres, FR;
Christophe Joussot-dubien, Rochefort du Gard, FR;
Jean-jacques Letourneau, Gragnague, FR;
Hubert Lochard, Albi, FR;
Florence Marciacq, Orgon, FR;
Martial Sauceau, Albi, FR;
Jacques Fages, Albi, FR;
Bernard Freiss, Castres, FR;
Christophe Joussot-Dubien, Rochefort du Gard, FR;
Jean-Jacques Letourneau, Gragnague, FR;
Hubert Lochard, Albi, FR;
Florence Marciacq, Orgon, FR;
Martial Sauceau, Albi, FR;
Pierre Fabre Medicament, Boulogne-Billancourt, FR;
Abstract
The invention concerns a method for preparing compounds for interaction of an active substance hardly soluble in an aqueous medium with a porous support. The invention is characterized in that it comprises the following steps: (a) mixing the active substance generated by supercritical fluid and the specific amount of porous support; (b) carrying out a molecular diffusion step by contacting in static mode a supercritical fluid with the mixture obtained at step (a) for the time required to improve the dissolution in the aqueous medium of the mixture obtained at step (a); (c) washing the interactive compound obtained at step (b) with a supercritical fluid flow; (d) recuperating the particles of the interactive compound thus formed. The invention also concerns a compound obtainable by said method.