The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2008
Filed:
Nov. 19, 2002
Arthur G. Romero, Kalamazoo, MI (US);
Heinrich J. Schostarez, Portage, MI (US);
Christina M. Roels, Battle Creek, MI (US);
Arthur G. Romero, Kalamazoo, MI (US);
Heinrich J. Schostarez, Portage, MI (US);
Christina M. Roels, Battle Creek, MI (US);
Phamacia & Upjohn Company LLC, Kalamazoo, MI (US);
Abstract
Disclosed are compounds of formula: and pharmaceutically acceptable salts and esters thereof, useful in treating and/or preventing Alzheimer's disease and other similar diseases, wherein R, R, R, n and Rare defined herein. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.