The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2008
Filed:
Apr. 04, 2007
Yong Seo Cho, Seoul, KR;
Hyunah Choo, Seoul, KR;
Joo Hwan Cha, Seoul, KR;
AE Nim Pae, Seoul, KR;
Satish N. Chavre, Seoul, KR;
Kyung IL Choi, Seoul, KR;
Yong Seo Cho, Seoul, KR;
Hyunah Choo, Seoul, KR;
Joo Hwan Cha, Seoul, KR;
Ae Nim Pae, Seoul, KR;
Satish N. Chavre, Seoul, KR;
Kyung Il Choi, Seoul, KR;
Korea Institute of Science and Technology, Seoul, KR;
Abstract
The present invention relates to a tetrahydrofuran compound having cis substituents, the derivatives thereof and a process for preparing the same, and in particular relates to a dihydrofuran-3-ylidene triflate compound having cis substituents at Cand Cpositions prepared through Prins-type cyclization using a homopropargylic alcohol derivative as a starting material in the presence of Lewis acid catalyst, a tetrahydrofuran compound having cis substituents at C, Cand Cpositions prepared through the hydrolysis of triflate group in the derivatives of the dihydrofuran-3-ylidene triflate compound, and a preparation method thereof. The derivatives and the target tetrahydrofuran compound prepared according to the present invention are hydrofuran compounds with novel structures having cis substituents at C, Cand/or Cpositions, which are useful as a derivative for synthesizing drugs such as an antagonist for neurokinin receptor.