The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2008

Filed:

Feb. 10, 2003
Applicants:

Kim J. Stutzman-engwall, East Lyme, CT (US);

Anke Krebber, Palo Alto, CA (US);

Claes Gustafsson, Belmont, CA (US);

Jeremy S. Minshull, Los Altos, CA (US);

Sun Ai Raillard, Mountain View, CA (US);

Seran Kim, Waukegan, IL (US);

Yan Chen, Santa Clara, CA (US);

Inventors:

Kim J. Stutzman-Engwall, East Lyme, CT (US);

Anke Krebber, Palo Alto, CA (US);

Claes Gustafsson, Belmont, CA (US);

Jeremy S. Minshull, Los Altos, CA (US);

Sun Ai Raillard, Mountain View, CA (US);

Seran Kim, Waukegan, IL (US);

Yan Chen, Santa Clara, CA (US);

Assignee:

Pfizer Inc, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12P 19/60 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of. The present invention further relates to vectors, host cells, and mutant strains ofin which the aveC gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.


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