The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2008

Filed:

Mar. 11, 2003
Applicants:

Norbert Schmees, Berlin, DE;

Manfred Lehmann, Berlin, DE;

Ulrike Fuhrmann, Berlin, DE;

Peter Muhn, Berlin, DE;

Christa Hegele-hartung, Muelheim/Ruhr, DE;

Michael Klotzbuecher, Berlin, DE;

Inventors:

Norbert Schmees, Berlin, DE;

Manfred Lehmann, Berlin, DE;

Ulrike Fuhrmann, Berlin, DE;

Peter Muhn, Berlin, DE;

Christa Hegele-Hartung, Muelheim/Ruhr, DE;

Michael Klotzbuecher, Berlin, DE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/502 (2006.01); A61K 31/536 (2006.01); C07D 237/32 (2006.01); C07D 265/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to non-steroidal progestins of the general formula (I) wherein or a pharmaceutically acceptable derivative or analogue thereof. These progestins are suitable for selectively modulating progesterone receptor mediated effects in different target tissues, particularly in uterine tissue versus breast tissue. Therefore, the progestins of the present invention, optionally in combination with estrogens, may be used for contraception (in particular in estrogen-free oral contraceptives), hormone replacement therapy and the treatment of gynecological disorders. The present invention furthermore relates to methods for selectively modulating progesterone receptor mediated effects in different target tissues or organs.


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