The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2008
Filed:
Feb. 24, 2005
Bo-lennart Johansson, Uppsala, SE;
Hans J. Johansson, Uppsala, SE;
Anders Ljunglöf, Uppsala, SE;
Jean-luc Maloisel, Uppsala, SE;
Nicolas Thevenin, Uppsala, SE;
Bo-Lennart Johansson, Uppsala, SE;
Hans J. Johansson, Uppsala, SE;
Anders Ljunglöf, Uppsala, SE;
Jean-Luc Maloisel, Uppsala, SE;
Nicolas Thevenin, Uppsala, SE;
GE Healthcare Bio-Sciences AB, Uppsala, SE;
Abstract
The present invention relates to a method of separating antibodies from contaminants in a solution, which method comprises contacting the solution with a chromatography resin comprised of a support to which multi-modal ligands have been immobilised, wherein a multi-modal ligand comprises at least one cation-exchanging group and at least one aromatic or heteroaromatic ring system. In one embodiment, the ring-forming atoms of the aromatic or hereoaromatic entity are selected among C, S or O, and the cation exchanging group is a weak cation exchanger. The present method may be used as a single step procedure or as a polishing step following a capture on a Protein A column.