The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2008

Filed:

Dec. 31, 2003
Applicants:

Scott Eugene Conner, Indianapolis, IN (US);

Nathan Bryan Mantlo, Brownsburg, IN (US);

Guoxin Zhu, Noblesville, IN (US);

Inventors:

Scott Eugene Conner, Indianapolis, IN (US);

Nathan Bryan Mantlo, Brownsburg, IN (US);

Guoxin Zhu, Noblesville, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/428 (2006.01); A61K 31/426 (2006.01); A61K 31/421 (2006.01); A61K 31/423 (2006.01); C07D 277/66 (2006.01); C07D 263/57 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compounds represented by the following structural formula, Formula I: wherein (a) X is selected from the group consisting of a single bond, O, S, S(O)and N; (b) U ia an aliphatic linker; (c) Y is selected from the group consisting of C, O, S, NH and a single bond; (d) E is C(R3) (R4) A or A and wherein (i) A is selected from the group consisting of carboxyl, tetrazole, C-Calkylnitrile, carboxamidek, sulfonamide and acylsulfonamide; (e) B is selected from the group consisting of S, O, C, and N; (f) Z is selected from the group consisting of N and C; with the proviso that when B is C then Z is N.


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