The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2008
Filed:
Jul. 24, 2002
Rachel Heulwen Reynolds, Loughborough, GB;
Anthony Howard Ingall, Loughborough, GB;
Rukhsana Tasneem Rasul, Loughborough, GB;
Simon David Guile, Loughborough, GB;
Martin Edward Cooper, Loughborough, GB;
Rachel Heulwen Reynolds, Loughborough, GB;
Anthony Howard Ingall, Loughborough, GB;
Rukhsana Tasneem Rasul, Loughborough, GB;
Simon David Guile, Loughborough, GB;
Martin Edward Cooper, Loughborough, GB;
AstraZeneca AB, , SE;
Abstract
The invention relates to a compound of formula (1); wherein: Rand Reach independently represent a Calkyl, Calkenyl, Ccycloalkyl Calkyl or Ccycloalkyl; each of which may be optionally substituted by 1 to 3 halogen atoms; Ris isoxyzolidin-2-ylcarbonyl or tetrahydroisoxazin-2-ylcarbonyl wherein each ring is optionally substituted by one hydroxy group; Q is CO— or C(R)(R)-(wherein Ris a hydrogen atom or Calkyl and Ris a hydrogen atom or hydroxy group); Ar is a 5- to 10-membered aromatic ring system wherein up to 4 ring atoms may be heteroatoms independently selected from nitrogen, oxygen and sulphur, the ring system being optionally substituted by one or more substituents as defined in the specification. It also relates to methods of preparing, pharmaceutical compositions containing and methods of using the compound of the formula (1), particularly in the modulation of autoimmune disease