The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2008
Filed:
Aug. 17, 2000
Douglas E. Brenneman, Damascus, MD (US);
Catherine Y. Spong, Arlington, VA (US);
Illana Gozes, Ramat Hasharon, IL;
Albert Pinhasov, Tel Aviv, IL;
Eliezer Giladi, Ramat Poleg, IL;
Douglas E. Brenneman, Damascus, MD (US);
Catherine Y. Spong, Arlington, VA (US);
Illana Gozes, Ramat Hasharon, IL;
Albert Pinhasov, Tel Aviv, IL;
Eliezer Giladi, Ramat Poleg, IL;
National Institute of Health, Rockville, MD (US);
Abstract
This invention provides an ADNF polypeptide comprising an active core site, the active core site comprising at least one D-amino acid. The invention also provides a pharmaceutical composition comprising an ADNF polypeptide comprising an active core site, the active core site comprising at least one D-amino acid. In particular, the pharmaceutical composition of the invention is orally active. The invention further provides methods for reducing neuronal cell death, methods for reducing oxidative stress, and methods for reducing a condition associated with fetal alcohol syndrome using the ADNF polypeptides and the pharmaceutical compositions of the invention.