The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2008
Filed:
Apr. 12, 2002
Robert John Zagursky, Victor, NY (US);
Amy Wadhams Masi, Caledonia, NY (US);
Bruce Arthur Green, New City, NY (US);
Deb Narayan Chakravarti, Claremont, CA (US);
David Parrish Russell, Canandaigua, NY (US);
Joseph Lawrence Wooters, Brighton, MA (US);
Robert John Zagursky, Victor, NY (US);
Amy Wadhams Masi, Caledonia, NY (US);
Bruce Arthur Green, New City, NY (US);
Deb Narayan Chakravarti, Claremont, CA (US);
David Parrish Russell, Canandaigua, NY (US);
Joseph Lawrence Wooters, Brighton, MA (US);
Wyeth, Madison, NJ (US);
Abstract
The present invention relates to newly identified open reading frames comprised within the genomic nucleotide sequence of, wherein the open reading frames encode polypeptides that are surface localized on. Thus, the invention relates toopen reading frames that encode polypeptide antigens, polypeptides, preferably antigenic polypeptides, encoded by theopen reading frames, vectors comprising open reading frame sequences and cells or animals transformed with these vectors. The invention relates also to methods of detecting these nucleic acids or polypeptides and kits for diagnosinginfection. The invention finally relates to pharmaceutical compositions, in particular immunogenic compositions, for the prevention and/or treatment of bacterial infection, in particular infections with. In particular embodiments, the immunogenic compositions are used for the treatment or prevention of systemic diseases which are induced or exacerbated by. In other embodiments, the immunogenic compositions are used for the treatment or prevention of non-systemic diseases, particularly of the otitis media, which are induced or exacerbated by