The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2008
Filed:
Feb. 02, 2006
Martha O'brien, Madison, WI (US);
Keith V. Wood, Mt. Horeb, WI (US);
Dieter Klaubert, Arroyo Grande, CA (US);
William Daily, Santa Maria, CA (US);
Martha O'Brien, Madison, WI (US);
Keith V. Wood, Mt. Horeb, WI (US);
Dieter Klaubert, Arroyo Grande, CA (US);
William Daily, Santa Maria, CA (US);
Promeaga Corporation, Madison, WI (US);
Abstract
A sensitive bioluminescent assay to detect proteases, including caspases and proteases that specifically cleave a peptide substrate having aspartate, is provided. In one embodiment, the assay employs an aminoluciferin or a carboxy-terminal protected derivative thereof covalently linked via a peptide bond to a substrate for a caspase or an aminoluciferin or a carboxy-terminal protected derivative thereof covalently linked via a peptide bond to a peptide substrate comprising aspartate that is specifically cleaved by a protease specific for the substrate.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile