The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2008
Filed:
May. 02, 2003
Masahiro Toda, Kanagawa, JP;
Yutaka Kawakami, Kanagawa, JP;
Yukihiko Iizuka, Rockville, MD (US);
Yoko Ueda, Kanagawa, JP;
Yoshihiro Iwahori, Tokyo, JP;
Masahiro Toda, Kanagawa, JP;
Yutaka Kawakami, Kanagawa, JP;
Yukihiko Iizuka, Rockville, MD (US);
Yoko Ueda, Kanagawa, JP;
Yoshihiro Iwahori, Tokyo, JP;
Institute of Gene and Brain Science, Tokyo, JP;
Abstract
It is intended to provide highly safe antitumor agents which exhibit an antitumor effect on human remote tumors such as metastatic tumors too and by which an antitumor immune reaction enabling an immune therapy for cancer can be induced, tumor immunity inducers, T cell activators, dendritic cell activators, a method of treating cancer using the same, etc. Inactivated herpes simplex virus (inactivated HSV), herpes simplex virus glycoprotein D (HSVgD), etc. are employed as the active ingredients of antitumor agents, tumor immunity inducers, T cell activators or dendritic cell activators. As a specific example of the treatment for the above-described inactivation, citation may be made of a combination of UV-irradiation using ultraviolet light at 254 nm at 4 J/mfor 30 minutes with heating at 56° C. for 30 minutes.