The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2008

Filed:

Feb. 11, 2000
Applicants:

Sun Ai Raillard, Mountain View, CA (US);

Yong Hong Chen, Foster City, CA (US);

Claus Krebber, Palo Alto, CA (US);

Jeremy Minshull, Los Altos, CA (US);

Willem P. C. Stemmer, Los Gatos, CA (US);

Inventors:

Sun Ai Raillard, Mountain View, CA (US);

Yong Hong Chen, Foster City, CA (US);

Claus Krebber, Palo Alto, CA (US);

Jeremy Minshull, Los Altos, CA (US);

Willem P. C. Stemmer, Los Gatos, CA (US);

Assignee:

Maxygen, Inc., Redwood City, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Apparatus and methods for high throughput mass spectrometry are provided. The methods involve sample preparation in an off-line parallel purification system. Such methods include but are not limited to the use of an appropriate buffer when generating samples or the use of a solid support for tagged components. The samples prepared in this way do not then need to be column separated. The apparatus provided includes a cell growth plate for growing cells and generating products and/or reactants, an off-line parallel purification system, a mass spectrometer, and an automatic sampler that transports samples and injects them into the mass spectrometer of the apparatus. The methods and apparatus described are used, for example, in screening enzyme reaction pathways.


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