The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2008

Filed:

Mar. 17, 2004
Applicants:

Jerome C. Bressi, San Diego, CA (US);

Jason W. Brown, San Diego, CA (US);

Sheldon X. Cao, San Diego, CA (US);

Anthony R. Gangloff, San Diego, CA (US);

Andrew J. Jennings, La Jolla, CA (US);

Jeffrey A. Stafford, San Diego, CA (US);

Phong H. VU, San Diego, CA (US);

Xiao-yi Xiao, San Diego, CA (US);

Inventors:

Jerome C. Bressi, San Diego, CA (US);

Jason W. Brown, San Diego, CA (US);

Sheldon X. Cao, San Diego, CA (US);

Anthony R. Gangloff, San Diego, CA (US);

Andrew J. Jennings, La Jolla, CA (US);

Jeffrey A. Stafford, San Diego, CA (US);

Phong H. Vu, San Diego, CA (US);

Xiao-Yi Xiao, San Diego, CA (US);

Assignee:

Takeda San Diego, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds that may be used to inhibit histone deacetylase having the formulaZ-Q-L-M or Z-L-Mwherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.


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