The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2008
Filed:
Mar. 17, 2005
Bruno Danieli, Milan, IT;
Pietro Delogu, Trieste, IT;
Sabrina DE Rosa, Cervignano del Friuli, IT;
Lorenza Fugazza, San Fiorano, IT;
Bruno Danieli, Milan, IT;
Pietro Delogu, Trieste, IT;
Sabrina De Rosa, Cervignano del Friuli, IT;
Lorenza Fugazza, San Fiorano, IT;
Serichim S.R.L., Torviscosa, IT;
Abstract
A new process is described for synthesising cyclohexanediacetic acid monoamide, a key compound in the synthesis of grabapentin precursors. The process of the invention is characterised by reacting cyclohexanone with cynoacetamide and immediately after, with a suitable malonic acid ester. A new intermediate (5-cyano-2,4-dioxo-3-azaspiro[5,5]undecane-1-carboxylic acid ester) is obtained which is convertible, under mild reaction conditions, into cyclohexanediacetic acid monoamide.