The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2008
Filed:
Oct. 22, 2004
Applicants:
Kohei Yamada, Choshi, JP;
Noritake Matsumoto, Habikino, JP;
Hiroyuki Hayakawa, Choshi, JP;
Inventors:
Assignee:
Yamasa Corporation, Choshi-shi, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); A01N 43/04 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for producing 2'-deoxy-2′-fluoro-β-D-arabinonucleoside represented by formula (II): (wherein B represents a base), in particular, 2′-deoxy-2′-fluoro-β-D-arabinopurinenucleoside, which method comprises causing a nucleoside phosphorylase to act on α-1-phosphorylated-2-deoxy-2-fluoroarabinoside represented by formula (I): or a mixture of α- and β-isomers of 1-phosphorylated-2-deoxy-2-fluoroarabinoside represented by formula (V′): and on a base. The compound can be produced at high yield and in a convenient and highly stereoselective manner.