The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2008
Filed:
Jul. 18, 2000
George Weiner, Iowa City, IA (US);
Roger Gingrich, Iowa City, IA (US);
Brian K. Link, Coralville, IA (US);
J. Yun Tso, Menlo Park, CA (US);
George Weiner, Iowa City, IA (US);
Roger Gingrich, Iowa City, IA (US);
Brian K. Link, Coralville, IA (US);
J. Yun Tso, Menlo Park, CA (US);
PDL BioPharma, Inc., Redwood City, CA (US);
Iowa Immunotherapy Investigators, Iowa City, IA (US);
Abstract
The invention provides bispecific antibodies with selective cytotoxicity against malignant B-cells. The bispecific antibodies bind to an effector cell antigen and to a 28/32 kDa heterodimeric protein on the surface of malignant B-cells. The invention also includes the monospecific components of the bispecific antibodies, humanized versions thereof, and humanized bispecific antibodies. The invention further provides therapeutic and diagnostic methods employing these antibodies.