The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2008
Filed:
Jul. 01, 2003
Applicants:
John R. Desjarlais, Pasadena, CA (US);
Rene S. Hubert, Los Angeles, CA (US);
Jamal El Yazal, Atla Loma, CA (US);
Shannon a Marshall, San Francisco, CA (US);
Inventors:
John R. Desjarlais, Pasadena, CA (US);
Rene S. Hubert, Los Angeles, CA (US);
Jamal El Yazal, Atla Loma, CA (US);
Shannon A Marshall, San Francisco, CA (US);
Assignee:
Xencor, Inc., Monrovia, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to novel, soluble, recombinant RANKL (Receptor Activator of Nuclear Factor—κB Ligand) variant proteins which may be expressed solubly in, variants that have substantially reduced binding to OPG, variants that act as RANKL antagonists, and methods for generating the same.