The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2008
Filed:
Jun. 09, 2005
James William Malecha, San Diego, CA (US);
Stewart Alwyn Noble, San Diego, CA (US);
Christian Andreus Hassig, Mira Mesa, CA (US);
Paul L. Wash, San Diego, CA (US);
Brandon M. Wiley, Philadelphia, PA (US);
Charles Maxwell Lawrence, San Diego, CA (US);
Timothy Z. Hoffman, San Diego, CA (US);
James William Malecha, San Diego, CA (US);
Stewart Alwyn Noble, San Diego, CA (US);
Christian Andreus Hassig, Mira Mesa, CA (US);
Paul L. Wash, San Diego, CA (US);
Brandon M. Wiley, Philadelphia, PA (US);
Charles Maxwell Lawrence, San Diego, CA (US);
Timothy Z. Hoffman, San Diego, CA (US);
Kalypsys, Inc., San Diego, CA (US);
Abstract
Disclosed herein are carbonyl compounds of having the structural formula: Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central nervous system disorders, neurodegenerative disorders, fibrosis, bone disorders, polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, cardiovascular conditions, and disorders in which angiogenesis play a role in pathogenesis, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.