The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2008

Filed:

Jun. 14, 2005
Applicants:

Huimin Zhao, Champaign, IL (US);

Ryan Woodyer, Champaign, IL (US);

Michael Simurdiak, Urbana, IL (US);

Wilfred A. Van Der Donk, Champaign, IL (US);

Inventors:

Huimin Zhao, Champaign, IL (US);

Ryan Woodyer, Champaign, IL (US);

Michael Simurdiak, Urbana, IL (US);

Wilfred A. van der Donk, Champaign, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/18 (2006.01); C12N 9/02 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

A new xylose reductase encoding gene fromwas heterologously expressed inas a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficiency, high stability at room temperature, broad pH profile, and a preference of NADPH over NADH. This enzyme is utilized in production of xylitol and other sugar alcohols such as sorbitol and also in the metabolic enhancement of organisms used for fermentation of plant biomass into ethanol.


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