The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2008

Filed:

May. 05, 2004
Applicants:

Hans-ulrich Demuth, Halle/Saale, DE;

Torsten Hoffmann, Halle/Saale, DE;

Andre J. Niestroj, Sennewitz, DE;

Stephan Schilling, Halle/Saale, DE;

Ulrich Heiser, Halle/Saale, DE;

Inventors:

Hans-Ulrich Demuth, Halle/Saale, DE;

Torsten Hoffmann, Halle/Saale, DE;

Andre J. Niestroj, Sennewitz, DE;

Stephan Schilling, Halle/Saale, DE;

Ulrich Heiser, Halle/Saale, DE;

Assignee:

Probiodrug AG, Weinbergweg 22, Halle Saale, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel physiological substrates of mammalian glutaminyl cyclase (QC, EC 2.3.2.5), new effectors of QC, methods for screeing for such effectors, and the use of such effectors and pharmaceutical compositions comprising such effectors for the treatment of conditions that can be treated by modulation of QC-activity. Preferred compositions additionally comprise inhibitors of DP IV or DP IV-like enzymes for the treatment or alleviation of conditions that can be treated by modulation of QC- and DP IV-activity.


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