The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2008

Filed:

Feb. 25, 2005
Applicants:

David Lewis, Parma, IT;

David Ganderton, Parma, IT;

Brian Meakin, Parma, IT;

Maurizio Delcanale, Parma, IT;

Fausto Pivetti, Parma, IT;

Inventors:

David Lewis, Parma, IT;

David Ganderton, Parma, IT;

Brian Meakin, Parma, IT;

Maurizio Delcanale, Parma, IT;

Fausto Pivetti, Parma, IT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/12 (2006.01); A61K 9/08 (2006.01); A61K 31/47 (2006.01); A61K 31/4704 (2006.01); A61M 11/00 (2006.01); A61M 11/04 (2006.01); A61M 15/00 (2006.01); A61M 15/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

Aerosol solution formulations for use in an aerosol inhaler which comprise 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]-ethyl]-2(1H)-quinolinone or a salt thereof, in particular the hydrochloride salt (TA 2005), as an active ingredient, a propellant containing a hydrofluoroalkane, and a cosolvent, stabilized by addition of a specific small amount of a high concentrated phosphoric acid exhibit improved shelf life. The formulation may be optionally contained in a can having part or all of its internal metallic surfaces lined with an inert organic coating.


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