The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2008
Filed:
Feb. 06, 2003
Applicants:
Steven F. Sukits, Arlington, MA (US);
Jean-baptiste Telliez, Waltham, MA (US);
Lih-ling Lin, Concord, MA (US);
Guang-yi Xu, Medford, MA (US);
Inventors:
Steven F. Sukits, Arlington, MA (US);
Jean-Baptiste Telliez, Waltham, MA (US);
Lih-Ling Lin, Concord, MA (US);
Guang-Yi Xu, Medford, MA (US);
Assignee:
Wyeth, Madison, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06F 19/00 (2006.01); A61K 38/00 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to the three dimensional solution structure of receptor interacting protein dead domain (RIP DD), as well as the identification and characterization of various binding active sites of RIP DD. Also provided for by the present invention are methods of utilizing the three dimensional structure for the design and selection of potent and selective inhibitors of TNF signaling pathways.