The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2008
Filed:
Dec. 02, 2004
Leslie M. Mcevoy, Mountain View, CA (US);
Christi Parham, Menlo Park, CA (US);
Jie Zhang, Campbell, CA (US);
Rolf Ehrhardt, Mill Valley, CA (US);
Leslie M. McEvoy, Mountain View, CA (US);
Christi Parham, Menlo Park, CA (US);
Jie Zhang, Campbell, CA (US);
Rolf Ehrhardt, Mill Valley, CA (US);
Anesiva, Inc., South San Francisco, CA (US);
Abstract
The present invention concerns double-stranded NF-κB decoy oligodeoxynucleotide (NF-κB dsODN) molecules that contain a core sequence capable of specific binding to an NF-κB transcription factor. In a particular aspect, the invention concerns NF-κB decoy molecules that preferentially bind p50/p65 and/or cRel/p50 heterodimers over p50/p50 homodimers. In another aspect, the invention concerns NF-κB decoy molecules with improved binding affinity to p65.