The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2008
Filed:
Jan. 30, 2003
Akira Ohhata, Mishima-gun, JP;
Yoshikazu Takaoka, Mishima-gun, JP;
Mikio Ogawa, Mishima-gun, JP;
Hisao Nakai, Mishima-gun, JP;
Susumu Yamamoto, Mishima-gun, JP;
Hiroshi Ochiai, Mishima-gun, JP;
Akira Ohhata, Mishima-gun, JP;
Yoshikazu Takaoka, Mishima-gun, JP;
Mikio Ogawa, Mishima-gun, JP;
Hisao Nakai, Mishima-gun, JP;
Susumu Yamamoto, Mishima-gun, JP;
Hiroshi Ochiai, Mishima-gun, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
A nitrogen-containing bicyclic compound of formula (I) or a pharmaceutically acceptable salt thereof (wherein the symbols have the same meanings as described in the specification). The compound of formula (I) has an inhibitory activity against PDE7 and it is useful for the prevention and/or treatment of various diseases, i.e. autoimmune diseases (ulcerative colitis, Crohn's disease, rheumatism, psoriasis, multiple sclerosis, collagenosis, etc.), inflammatory diseases (obstructive pulmonary disease, sepsis, pancreatitis, sarcoidosis, nephritis, hepatitis, enteritis, etc.), allergic diseases (asthma, allergic rhinitis, allergic conjunctivitis, seasonal conjunctivitis, atopic dermatitis, etc.), rejection of organ transplants, serious graft versus host disease (GVHD), diabetic disease, osteoporosis, bone fracture, restenosis, atherosclerosis, obesity, ischemic reperfusion injury, depression, Parkinson's disease, dementia, leukemia, etc.